Acetaminophen → HCID 11553485, compound

HRID 1173386Notes

Reaction equation

HRID 1173386 reaction equation
[CH:1]1([CH2:4][N:5]([CH2:18][CH2:19][OH:20])[C:6]2[CH:13]=[CH:12][C:9]([C:10]#[N:11])=[C:8]([C:14]([F:17])([F:16])[F:15])[CH:7]=2)[CH2:3][CH2:2]1.[C:21]([NH:24][C:25]1[CH:30]=[CH:29][C:28](O)=[CH:27][CH:26]=1)(=[O:23])[CH3:22]>>[C:10]([C:9]1[CH:12]=[CH:13][C:6]([N:5]([CH2:4][CH:1]2[CH2:2][CH2:3]2)[CH2:18][CH2:19][O:20][C:28]2[CH:29]=[CH:30][C:25]([NH:24][C:21](=[O:23])[CH3:22])=[CH:26][CH:27]=2)=[CH:7][C:8]=1[C:14]([F:16])([F:17])[F:15])#[N:11]

Participants

3

Reactant 2

HCID 1983AcetaminophenHCID 11369616HCID 11369616, compound

Product 1

HCID 11553485HCID 11553485, compound

Procedure

Synthesized as described in Example 1C from 4-[(cyclopropylmethyl)(2-hydroxyethyl)amino]-2-(trifluoromethyl)benzonitrile and 4-acetamidophenol: MS (APCI) m/z 418 (M+1).

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-6abd1b7066ce4d1fb4eada90d84e6a89
Source dataset
uspto-grants-2010_11
Patent number
US07834063B2

Reaction notes

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