4-Fluorophenol → HCID 11581656, compound

HRID 1173388Notes

Reaction equation

HRID 1173388 reaction equation
[CH:1]1([CH2:4][N:5]([CH2:18][CH2:19][OH:20])[C:6]2[CH:13]=[CH:12][C:9]([C:10]#[N:11])=[C:8]([C:14]([F:17])([F:16])[F:15])[CH:7]=2)[CH2:3][CH2:2]1.[F:21][C:22]1[CH:27]=[CH:26][C:25](O)=[CH:24][CH:23]=1>>[CH:1]1([CH2:4][N:5]([CH2:18][CH2:19][O:20][C:25]2[CH:26]=[CH:27][C:22]([F:21])=[CH:23][CH:24]=2)[C:6]2[CH:13]=[CH:12][C:9]([C:10]#[N:11])=[C:8]([C:14]([F:16])([F:17])[F:15])[CH:7]=2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 97324-FluorophenolHCID 11369616HCID 11369616, compound

Product 1

HCID 11581656HCID 11581656, compound

Procedure

Synthesized as described in Example 1C from 4-[(cyclopropylmethyl)(2-hydroxyethyl)amino]-2-(trifluoromethyl)benzonitrile and 4-fluorophenol: MS (APCI) m/z 379 (M+1).

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-19c0db970f5c4c1c89d5f4b60b5de09d
Source dataset
uspto-grants-2010_11
Patent number
US07834063B2

Reaction notes

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