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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1173401Generated: October 31, 2026

4-Fluorophenol → 4-[{3-[(4-Fluorophenyl)oxy]propyl}(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile

https://huagongshe.com/reaction/1173401

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluorophenolHCID 9732—
Reactant4-[(3-Hydroxypropyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrileHCID 86606248—
Product4-[{3-[(4-Fluorophenyl)oxy]propyl}(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrileHCID 11546262—

Reaction Steps

Synthesized as described in Example 1C from 4-[(3-hydroxypropyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile and 4-fluorophenol: MS (ES) m/z 421 (M+1)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07834063B2
Source datasetuspto-grants-2010_11
ORD IDord-4463397ff0fc407385a7f97e81a844eb
Source noteuspto-grants-2010_11