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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1173402Generated: October 30, 2026

4-Methoxyphenol → 4-[(3-{[4-(Methyloxy)phenyl]oxy}propyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile

https://huagongshe.com/reaction/1173402

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethoxyphenolHCID 9015—
Reactant4-[(3-Hydroxypropyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrileHCID 86606248—
Product4-[(3-{[4-(Methyloxy)phenyl]oxy}propyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrileHCID 11718980—

Reaction Steps

Synthesized as described in Example 1C from 4-[(3-hydroxypropyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile and 4-methoxyphenol: MS (ESI) m/z 433 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07834063B2
Source datasetuspto-grants-2010_11
ORD IDord-9fbd2c34203340c4b7ce618233b15395
Source noteuspto-grants-2010_11