HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorophenol → 4-[{2-[(4-Fluorophenyl)oxy]ethyl}(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorophenol | HCID 9732 | — |
| Reactant | 4-[(2-Hydroxyethyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile | HCID 86623731 | — |
| Product | 4-[{2-[(4-Fluorophenyl)oxy]ethyl}(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile | HCID 11618356 | — |
Reaction Steps
Synthesized as described in Example 1C using 4-[(2-hydroxyethyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile and 4-fluorophenol: MS (El) m/z 406 (M+, 54%), 295 ([M-C6H4FO]+, 82%), 281 (100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07834063B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-f289b4bab37a4ebcb32536f290002ac2 |
| Source note | uspto-grants-2010_11 |