4'-Hydroxyacetophenone → HCID 11618840, compound

HRID 1173414Notes

Reaction equation

HRID 1173414 reaction equation
[OH:1][CH2:2][CH2:3][N:4]([CH2:17][C:18]([F:21])([F:20])[F:19])[C:5]1[CH:12]=[CH:11][C:8]([C:9]#[N:10])=[C:7]([C:13]([F:16])([F:15])[F:14])[CH:6]=1.[CH3:22][C:23]([C:25]1[CH:26]=[CH:27][C:28](O)=[CH:29][CH:30]=1)=[O:24]>>[C:23]([C:25]1[CH:26]=[CH:27][C:28]([O:1][CH2:2][CH2:3][N:4]([CH2:17][C:18]([F:19])([F:20])[F:21])[C:5]2[CH:12]=[CH:11][C:8]([C:9]#[N:10])=[C:7]([C:13]([F:15])([F:16])[F:14])[CH:6]=2)=[CH:29][CH:30]=1)(=[O:24])[CH3:22]

Participants

3

Reactant 2

HCID 74694'-HydroxyacetophenoneHCID 866237314-[(2-Hydroxyethyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile

Product 1

HCID 11618840HCID 11618840, compound

Procedure

Synthesized as described in Example 1C using 4-[(2-hydroxyethyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile and 4-hydroxyacetophenone: MS (APCI) m/z 431 (M+1).

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-dfb5b91d61d1470da3b1b1c8420d1726
Source dataset
uspto-grants-2010_11
Patent number
US07834063B2

Reaction notes

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