4-Hydroxyphenylacetone → HCID 11640831, compound

HRID 1173415Notes

Reaction equation

HRID 1173415 reaction equation
[OH:1][CH2:2][CH2:3][N:4]([CH2:17][C:18]([F:21])([F:20])[F:19])[C:5]1[CH:12]=[CH:11][C:8]([C:9]#[N:10])=[C:7]([C:13]([F:16])([F:15])[F:14])[CH:6]=1.O[C:23]1[CH:28]=[CH:27][C:26]([CH2:29][C:30](=[O:32])[CH3:31])=[CH:25][CH:24]=1>>[O:32]=[C:30]([CH3:31])[CH2:29][C:26]1[CH:27]=[CH:28][C:23]([O:1][CH2:2][CH2:3][N:4]([CH2:17][C:18]([F:19])([F:20])[F:21])[C:5]2[CH:12]=[CH:11][C:8]([C:9]#[N:10])=[C:7]([C:13]([F:15])([F:16])[F:14])[CH:6]=2)=[CH:24][CH:25]=1

Participants

3

Reactant 2

HCID 70192744-HydroxyphenylacetoneHCID 866237314-[(2-Hydroxyethyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile

Product 1

HCID 11640831HCID 11640831, compound

Procedure

Synthesized as described in Example 1C using 4-[(2-hydroxyethyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile and 1-(4-hydroxyphenyl)-2-propanone: MS (APCI) m/z 445 (M+1).

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-e9edff8e83a94a74acefd8afb942fc4d
Source dataset
uspto-grants-2010_11
Patent number
US07834063B2

Reaction notes

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