3-Hydroxyacetanilide → HCID 11568490, compound

HRID 1173416Notes

Reaction equation

HRID 1173416 reaction equation
[OH:1][CH2:2][CH2:3][N:4]([CH2:17][C:18]([F:21])([F:20])[F:19])[C:5]1[CH:12]=[CH:11][C:8]([C:9]#[N:10])=[C:7]([C:13]([F:16])([F:15])[F:14])[CH:6]=1.[C:22]([NH:25][C:26]1[CH:27]=[C:28](O)[CH:29]=[CH:30][CH:31]=1)(=[O:24])[CH3:23]>>[C:9]([C:8]1[CH:11]=[CH:12][C:5]([N:4]([CH2:17][C:18]([F:19])([F:20])[F:21])[CH2:3][CH2:2][O:1][C:30]2[CH:31]=[C:26]([NH:25][C:22](=[O:24])[CH3:23])[CH:27]=[CH:28][CH:29]=2)=[CH:6][C:7]=1[C:13]([F:15])([F:16])[F:14])#[N:10]

Participants

3

Reactant 2

HCID 121243-HydroxyacetanilideHCID 866237314-[(2-Hydroxyethyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile

Product 1

HCID 11568490HCID 11568490, compound

Procedure

Synthesized as described in Example 1C using 4-[(2-hydroxyethyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile and 3-acetamidophenol: MS (APCI) m/z 446 (M+1).

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-1450d90d10cd43f2876f48c8ae9c83f6
Source dataset
uspto-grants-2010_11
Patent number
US07834063B2

Reaction notes

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