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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1173442Generated: October 31, 2026

5-Fluoro-2-hydroxypyridine → HCID 11718416, compound

https://huagongshe.com/reaction/1173442

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Fluoro-2-hydroxypyridineHCID 2762864—
Reactant4-[(2-Hydroxyethyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrileHCID 86623731—
Solvent1,2-DimethoxyethaneHCID 8071—
ProductHCID 11718416HCID 11718416—

Reaction Steps

Synthesized as described in Example 27B from 4-[(2-hydroxyethyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile (Example 15B) and 5-fluoro-2(1H)-pyridinone, using dry DME as the reaction solvent: MS (APCI) m/z 408 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07834063B2
Source datasetuspto-grants-2010_11
ORD IDord-aa672551957849d385d812c2059fb18e
Source noteuspto-grants-2010_11