HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-{6-[(Phenylmethyl)oxy]-3-pyridinyl}acetamide → HCID 178474274, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-{6-[(Phenylmethyl)oxy]-3-pyridinyl}acetamide | HCID 59557134 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178474274 | HCID 178474274 | 99.7% |
Reaction Steps
To a solution of N-{6-[(phenylmethyl)oxy]-3-pyridinyl}acetamide (0.210 g, 0.87 mmol) in EtOH (10 mL) at rt was added Pd—C (0.046 g of 10 wt % on activated carbon (dry basis), ca. 50 wt % H2O; ca. 0.022 mmol Pd). The mixture was placed under an atmosphere of H2 and stirred for 4.5 h. The mixture was filtered through Celite (EtOAc wash) and concentrated in vacuo, affording 0.132 g of the title compound as a colorless solid: MS (ESI) m/z 152 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07834063B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-6253c988063c46f6b92abd8d073f19a3 |
| Source note | uspto-grants-2010_11 |