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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1173446Generated: October 31, 2026

N-{6-[(Phenylmethyl)oxy]-3-pyridinyl}acetamide → HCID 178474274, compound

https://huagongshe.com/reaction/1173446

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-{6-[(Phenylmethyl)oxy]-3-pyridinyl}acetamideHCID 59557134—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 178474274HCID 17847427499.7%

Reaction Steps

To a solution of N-{6-[(phenylmethyl)oxy]-3-pyridinyl}acetamide (0.210 g, 0.87 mmol) in EtOH (10 mL) at rt was added Pd—C (0.046 g of 10 wt % on activated carbon (dry basis), ca. 50 wt % H2O; ca. 0.022 mmol Pd). The mixture was placed under an atmosphere of H2 and stirred for 4.5 h. The mixture was filtered through Celite (EtOAc wash) and concentrated in vacuo, affording 0.132 g of the title compound as a colorless solid: MS (ESI) m/z 152 (M+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07834063B2
Source datasetuspto-grants-2010_11
ORD IDord-6253c988063c46f6b92abd8d073f19a3
Source noteuspto-grants-2010_11