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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1173458Generated: October 30, 2026

4-Methoxyphenol → 4-[(2,2-Dimethylpropyl)(3-{[4-(methyloxy)phenyl]oxy}propyl)amino]-2-(trifluoromethyl)benzonitrile

https://huagongshe.com/reaction/1173458

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethoxyphenolHCID 9015—
Reactant4-[(2,2-Dimethylpropyl)(3-hydroxypropyl)amino]-2-(trifluoromethyl)benzonitrileHCID 11347554—
Product4-[(2,2-Dimethylpropyl)(3-{[4-(methyloxy)phenyl]oxy}propyl)amino]-2-(trifluoromethyl)benzonitrileHCID 11553545—

Reaction Steps

Synthesized as described in Example 1C from 4-[(2,2-dimethylpropyl)(3-hydroxypropyl)amino]-2-(trifluoromethyl)benzonitrile and 4-methoxyphenol: MS (ESI) m/z 421 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07834063B2
Source datasetuspto-grants-2010_11
ORD IDord-7c571e6c37d242f098be362bc7db629e
Source noteuspto-grants-2010_11