Acetaminophen → HCID 44529280, compound

HRID 1173473Notes

Reaction equation

HRID 1173473 reaction equation
[OH:1][CH2:2][CH2:3][N:4]([CH2:17][C:18]([F:21])([F:20])[F:19])[C:5]1[CH:12]=[CH:11][C:8]([C:9]#[N:10])=[CH:7][C:6]=1[C:13]([F:16])([F:15])[F:14].[C:22]([NH:25][C:26]1[CH:31]=[CH:30][C:29](O)=[CH:28][CH:27]=1)(=[O:24])[CH3:23]>>[C:9]([C:8]1[CH:11]=[CH:12][C:5]([N:4]([CH2:17][C:18]([F:19])([F:20])[F:21])[CH2:3][CH2:2][O:1][C:29]2[CH:30]=[CH:31][C:26]([NH:25][C:22](=[O:24])[CH3:23])=[CH:27][CH:28]=2)=[C:6]([C:13]([F:15])([F:16])[F:14])[CH:7]=1)#[N:10]

Participants

3

Reactant 2

HCID 1983AcetaminophenHCID 86623738HCID 86623738, compound

Product 1

HCID 44529280HCID 44529280, compound

Procedure

Synthesized as described in Example 1C from 4-[(2-hydroxyethyl)(2,2,2-trifluoroethyl)amino]-3-(trifluoromethyl)benzonitrile and 4-acetamidophenol: MS (APCI) m/z 446 (M+1).

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-9f7b18dd4eff4bf0b3326ea36af5ce64
Source dataset
uspto-grants-2010_11
Patent number
US07834063B2

Reaction notes

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