4-Fluorophenol → HCID 11647135, compound

HRID 1173474Notes

Reaction equation

HRID 1173474 reaction equation
[OH:1][CH2:2][CH2:3][N:4]([CH2:17][C:18]([F:21])([F:20])[F:19])[C:5]1[CH:12]=[CH:11][C:8]([C:9]#[N:10])=[CH:7][C:6]=1[C:13]([F:16])([F:15])[F:14].[F:22][C:23]1[CH:28]=[CH:27][C:26](O)=[CH:25][CH:24]=1>>[F:22][C:23]1[CH:28]=[CH:27][C:26]([O:1][CH2:2][CH2:3][N:4]([CH2:17][C:18]([F:19])([F:20])[F:21])[C:5]2[CH:12]=[CH:11][C:8]([C:9]#[N:10])=[CH:7][C:6]=2[C:13]([F:15])([F:16])[F:14])=[CH:25][CH:24]=1

Participants

3

Reactant 2

HCID 97324-FluorophenolHCID 86623738HCID 86623738, compound

Product 1

HCID 11647135HCID 11647135, compound

Procedure

Synthesized as described in Example 1C from 4-[(2-hydroxyethyl)(2,2,2-trifluoroethyl)amino]-3-(trifluoromethyl)benzonitrile and 4-fluorophenol: MS (APCI) m/z 407 (M+1).

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-5887f152c07c4ff68aa9326568d2d37d
Source dataset
uspto-grants-2010_11
Patent number
US07834063B2

Reaction notes

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