HuagongsheHuagongshe Chemistry Print Report · For research reference only
Allyl bromide → 4-[2-Propen-1-yl(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Allyl bromide | HCID 7841 | — |
| Reactant | 4-((2,2,2-Trifluoroethyl)amino)-2-(trifluoromethyl)benzonitrile | HCID 43138537 | — |
| Product | 4-[2-Propen-1-yl(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile | HCID 86239513 | — |
Reaction Steps
Synthesized according to Example 61A using 4-(2,2,2-trifluoro-ethylamino)-2-trifluoromethyl-benzonitrile and allyl bromide: 1H NMR (300 MHz, CDCl3) δ 7.65 (d, J=8.8 Hz, 1H), 7.07 (d, J=2.4 Hz, 1H), 6.93 (dd, J=8.8, 2.6 Hz, 1H), 5.80 (ddt, J=17.2, 10.4, 5.0 Hz, 1H), 5.31 (app. d, J=10.6 Hz, 1H), 5.14 (app. d, J=17.2 Hz, 1H), 4.19-4.11 (m, 2H), 3.98 (q, J=8.6 Hz, 2H); MS (APCI) m/z 309 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07834063B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-85ecad94736f4fe282559ac705518ee0 |
| Source note | uspto-grants-2010_11 |