1-Phenethylamine, (-)- → HCID 11668233, compound

HRID 1173497Notes

Reaction equation

HRID 1173497 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([N:9]([CH2:14][CH2:15][CH3:16])[CH2:10][C:11]([OH:13])=O)=[CH:5][C:4]=1[C:17]([F:20])([F:19])[F:18])#[N:2].[C:21]1([C@@H:27]([NH2:29])[CH3:28])[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[C:1]([C:3]1[CH:8]=[CH:7][C:6]([N:9]([CH2:14][CH2:15][CH3:16])[CH2:10][C:11]([NH:29][C@H:27]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH3:28])=[O:13])=[CH:5][C:4]=1[C:17]([F:20])([F:19])[F:18])#[N:2]

Participants

3

Reactant 2

HCID 758181-Phenethylamine, (-)-HCID 11243130HCID 11243130, compound

Product 1

HCID 11668233HCID 11668233, compound

Procedure

Synthesized as described for Example 91C using N-[4-cyano-3-(trifluoromethyl)phenyl]-N-propylglycine and (1S)-1-phenylethanamine: MS (APCI) m/z 390 (M+1).

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-fe0a29c76e5349d58643e872792d758c
Source dataset
uspto-grants-2010_11
Patent number
US07834063B2

Reaction notes

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