Cyclopropanemethanamine → N-(cyclopropylmethyl)-4-nitro-3-(trifluoromethyl)aniline

HRID 1173515Notes

Reaction equation

HRID 1173515 reaction equation
F[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[C:4]([C:11]([F:14])([F:13])[F:12])[CH:3]=1.[CH:15]1([CH2:18][NH2:19])[CH2:17][CH2:16]1>>[CH:15]1([CH2:18][NH:19][C:2]2[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[C:4]([C:11]([F:14])([F:13])[F:12])[CH:3]=2)[CH2:17][CH2:16]1

Participants

3

Reactant 2

HCID 75646CyclopropanemethanamineHCID 2230945-Fluoro-2-nitrobenzotrifluoride

Product 1

HCID 11391299N-(cyclopropylmethyl)-4-nitro-3-(trifluoromethyl)aniline

Procedure

Synthesized as described in Example 1A from 4-fluoro-1-nitro-2-(trifluoromethyl)benzene and (cyclopropylmethyl)amine: MS (APCI) m/z 261 (M+1).

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-b023eef2c8974dec9e0e16d0c47505a0
Source dataset
uspto-grants-2010_11
Patent number
US07834063B2

Reaction notes

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