Cyclopropanemethanamine → 4-[(Cyclopropylmethyl)amino]-3-(trifluoromethyl)benzonitrile

HRID 1173516Notes

Reaction equation

HRID 1173516 reaction equation
F[C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][C:3]=1[C:10]([F:13])([F:12])[F:11].[CH:14]1([CH2:17][NH2:18])[CH2:16][CH2:15]1>>[CH:14]1([CH2:17][NH:18][C:2]2[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][C:3]=2[C:10]([F:13])([F:12])[F:11])[CH2:16][CH2:15]1

Participants

3

Reactant 2

HCID 75646CyclopropanemethanamineHCID 1442554-Fluoro-3-(trifluoromethyl)benzonitrile

Product 1

HCID 112878954-[(Cyclopropylmethyl)amino]-3-(trifluoromethyl)benzonitrile

Procedure

Synthesized as described in Example 1A from 4-fluoro-3-(trifluoromethyl)benzonitrile and (cyclopropylmethyl)amine: MS (APCI) m/z 241 (M+1).

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-28e4600954fe42e69220f9361a4627c0
Source dataset
uspto-grants-2010_11
Patent number
US07834063B2

Reaction notes

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