HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → HCID 59556966, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 1,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine) | HCID 636044 | — |
| Reactant | 4-Bromo-2-methoxybenzonitrile | HCID 22346702 | — |
| Reactant | HCID 58238347 | HCID 58238347 | — |
| Catalyst | Bis(dibenzylideneacetone)palladium | HCID 9811564 | — |
| Product | HCID 59556966 | HCID 59556966 | — |
Reaction Steps
Using (6S)-7-(tert-butyldimethylsilyloxy)-6-methyl-5-azaspiro[2.4]heptan-4-one (762.2 mg), 4-bromo-2-methoxybenzonitrile (724 mg), cesium carbonate (1.46 g), tris(dibenzylideneacetone)dipalladium(0) (136.6 mg) and 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene (345.3 mg), and in the same manner as in Reference Example 3, the title compound was obtained as a colorless solid (yield: 760 mg, 66%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07834051B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-10d35d404d9442dcaec480b4e6167395 |
| Source note | uspto-grants-2010_11 |