Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 21669598 | HCID 21669598 | — |
| Solvent | tert-Butyl methyl ether | HCID 15413 | — |
| Product | HCID 10909830 | HCID 10909830 | 104.9% |
Reaction Steps
Ethyl (2R,3R)-2-chloro-3-hydroxyhexanoate (1.0 g, 5 mmol), ethanol (10 ml) and potassium carbonate (2.1 g, 15 mmol) were mixed, and the mixture was stirred at 15° C. for 14 hours. Methyl tert-butyl ether (20 ml) was added. The mixture was washed with water (10 ml) three times. The organic layer was concentrated under reduced pressure to obtain the title compound (0.83 g, yield: 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07834190B2 |
|---|
| Source dataset | uspto-grants-2010_11 |
|---|
| ORD ID | ord-a0e2ece933e3448495c9834afd1870b6 |
|---|
| Source note | uspto-grants-2010_11 |
|---|
