Acetophenone → 1-Phenylethanol

Participants

Reaction Steps

Specifically with respect to acetophenone, a resealable NMR tube containing a solution of the catalyst (11.8 mg, 30 μmol) and acetophenone (3.5 μL, 30 μmol) in preferred non-reactive solvent toluene (500 μL) was monitored by 1H NMR spectroscopy over days. After 12 h, about 28% of the catalyst had been converted. Extended reaction times resulted in unidentified decomposition products and free 1-phenylethanol. A similar reaction with acetone generated the mixture of the catalyst and the expected alcohol.

Provenance & Evidence