Bis(4-nitrophenyl) carbonate → HCID 42625373, compound

Participants

Reaction Conditions

Reaction Steps

A solution of the product from Example 17C (10.27 g, 27.1 mmol), bis (4-nitrophenyl) carbonate (8.24 g, 27.1 mmol), in toluene (100 mL) was heated at 110° C. for 16 hours, cooled to 25° C., treated with 1M sodium bicarbonate, and extracted with ethyl acetate. The organic phase layer was concentrated and the residue was purified by flash chromatography on silica gel eluting with 60% ethyl acetate in hexane to give the title compound as a white solid (9.44 g, 64% yield).

Provenance & Evidence