Hydrochloric Acid → HCID 72942063, compound

Participants

Reaction Conditions

Reaction Steps

A solution of the product of Example 59B (0.2 g) in tetrahydrofuran (0.2 mL) was treated with 30% HCl (0.2 mL), stirred at 75° C. for 6 hours, cooled to 25° C. and concentrated. The residue was partitioned between 10% NaHCO3 and ethyl acetate, the organic phase layer was separated and washed with brine, dried over Na2SO4, filtered and concentrated to give the title compound (175 mg).

Provenance & Evidence