3-[(4-Chlorophenyl)(cyclopropyl)methyl]-7-[(methylsulfanyl)methyl]-1H-indole → 3-[Cyclopropyl(2,4-difluorophenyl)methyl]-7-[(methylsulfanyl)methyl]-1H-indole
Reaction equation
[CH3:1][S:2][CH2:3][c:4]1[cH:5][cH:6][cH:7][c:8]2[cH:9][cH:10][nH:11][c:12]12.[CH:13]1([CH:16]([OH:17])[c:18]2[c:19]([F:25])[cH:20][c:21]([F:24])[cH:22][cH:23]2)[CH2:14][CH2:15]1.[Cl:26][c:27]1[cH:28][cH:29][c:30]([CH:31]([CH:32]2[CH2:33][CH2:34]2)[c:35]2[c:36]3[c:37]([c:38]([CH2:39][S:40][CH3:41])[cH:42][cH:43][cH:44]3)[nH:45][cH:46]2)[cH:47][cH:48]1>>[CH3:1][S:2][CH2:3][c:4]1[cH:5][cH:6][cH:7][c:8]2[c:9]([CH:16]([CH:13]3[CH2:14][CH2:15]3)[c:18]3[c:19]([F:25])[cH:20][c:21]([F:24])[cH:22][cH:23]3)[cH:10][nH:11][c:12]12Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-cc52184087f04fe1b401259211159f1e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…