HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1174279Generated: November 2, 2026
Hydrochloric Acid → benzyl (1S,2S,4S)-4-amino-2-hydroxy-5-phenyl-1-[4-(3-pyridinyl)benzyl]pentylcarbamate
https://huagongshe.com/reaction/1174279
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | benzyl (4S,5S)-5-{(2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl}-2,2-dimethyl-4-[4-(3-pyridinyl)benzyl]-1,3-oxazolidine-3-carboxylate | HCID 56594883 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | benzyl (1S,2S,4S)-4-amino-2-hydroxy-5-phenyl-1-[4-(3-pyridinyl)benzyl]pentylcarbamate | HCID 56594885 | — |
Reaction Steps
A solution containing the product from Example 67A (0.059 g, 0.093 mmol) in a mixture of methanol (3 mL) and aqueous HCl (1 mL, 1 N) was stirred at 50° C. for 2 hours, and concentrated to give the title compound as the hydrochloride salt, which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07834043B2 |
|---|
| Source dataset | uspto-grants-2010_11 |
|---|
| ORD ID | ord-b0844637654f48dab4f3cb6d2dd098d6 |
|---|
| Source note | uspto-grants-2010_11 |
|---|
