HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1174287Generated: November 1, 2026
Trifluoroacetic acid → HCID 90822597, compound
https://huagongshe.com/reaction/1174287
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Tert-butyl (1s,2r,4r)-1-benzyl-2-hydroxy-4-({(2s)-2-[(methoxycarbonyl)amino]-3,3-dimethylbutanoyl}amino)-5-[4-(2-pyridinyl)phenyl]pentylcarbamate | HCID 91154381 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 90822597 | HCID 90822597 | — |
Reaction Steps
A solution containing the product from Example 107G (0.042 g, 0.066 mmol) in dichloromethane (1 mL) was treated with trifluoroacetic acid (1 mL), stirred at 25° C. for 1 hour, concentrated, and partitioned between ethyl acetate and saturated NaHCO3 solution. The organic phase was washed with brine, dried over MgSO4, filtered and concentrated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07834043B2 |
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| Source dataset | uspto-grants-2010_11 |
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| ORD ID | ord-53974101629f4eed9d69b794ed15c189 |
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| Source note | uspto-grants-2010_11 |
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