Water → HCID 20709528, compound

Participants

Reaction Conditions

Reaction Steps

A solution containing the product from Example 115D (1.1 g, 5.3 mmol) in THF (20 mL) at −30° C. was treated with a solution of lithium aluminum hydride (5.3 mL, 1 M in THF), stirred at −30° C. for 5 minutes, treated with water (0.20 mL), 15% NaOH (0.20 mL), and water (0.40 mL) sequentially, stirred for 15 minutes at 25° C., filtered, rinsed with ethyl acetate, and concentrated to give the title compound (0.88 g, quantitative).

Provenance & Evidence