反应详情

A solution of 3-methyl-2-nitrobenzyl alcohol (0.4 g, 2.4 mmol) in acetonitrile (8 mL) was treated with Dess-Martin reagent (1.11 g, 2.63 mmol) at 25° C. for 16 h. The mixture was quenched with sodium bicarbonate/sodium thiosulfate (1:1, 15 mL), and the mixture was extracted with dichloromethane, the organic layer separated, washed with brine, dried over sodium sulfate, filtered, and the solvents were evaporated to give the crude title compound (0.387 g, 98%).

1. customThe mixture was quenched with sodium bicarbonate/sodium thiosulfate (1:1, 15 mL)
2. extractionthe mixture was extracted with dichloromethane
3. customthe organic layer separated
4. washwashed with brine
5. dry with materialdried over sodium sulfate
6. filtrationfiltered
7. customthe solvents were evaporated