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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1174384Generated: October 31, 2026

Trifluoroacetic acid → (αS)-α-(1,1-Dimethylethyl)-2-oxo-1-imidazolidineacetic acid

https://huagongshe.com/reaction/1174384

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 67406576HCID 67406576—
SolventDichloromethaneHCID 6344—
Product(αS)-α-(1,1-Dimethylethyl)-2-oxo-1-imidazolidineacetic acidHCID 20682363—

Reaction Steps

To a solution containing the product from Example 160A (0.050 g, 0.195 mmol) in dichloromethane (1.0 mL) was added trifluoracetic acid (1.0 mL), and the mixture was stirred at room temperature for 2 hours. The solvent was evaporated and the residue was triturated with ether to give a white solid, which was collected by filtration and used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07834043B2
Source datasetuspto-grants-2010_11
ORD IDord-edcb6dfbfb7d43bca5e15fe488d6c8d3
Source noteuspto-grants-2010_11