HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → (αS)-α-(1,1-Dimethylethyl)-2-oxo-1-imidazolidineacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 67406576 | HCID 67406576 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | (αS)-α-(1,1-Dimethylethyl)-2-oxo-1-imidazolidineacetic acid | HCID 20682363 | — |
Reaction Steps
To a solution containing the product from Example 160A (0.050 g, 0.195 mmol) in dichloromethane (1.0 mL) was added trifluoracetic acid (1.0 mL), and the mixture was stirred at room temperature for 2 hours. The solvent was evaporated and the residue was triturated with ether to give a white solid, which was collected by filtration and used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07834043B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-edcb6dfbfb7d43bca5e15fe488d6c8d3 |
| Source note | uspto-grants-2010_11 |