1-Butanaminium, N,N,N-tributyl-, azide → (S)-3-Azido-4,4-dimethyldihydrofuran-2(3H)-one

Beteiligte Stoffe

Reaktionsschritte

To a solution containing the product from Example 174A (4.6 g, 17.56 mmol) in toluene (80.0 mL) was added tetra-n-butylammonium azide (5.0 g, 17.57 mmol) at room temperature, and the mixture was stirred for 5 hours. The reaction was diluted with ether and washed with water, dilute NaHCO3, 10% citric acid and brine. The organic layer was dried over MgSO4, filtered and concentrated to give the crude product, which was used without further purification (2.79 g).

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