Lithium Carbonate → HCID 67426523, compound

Participants

Reaction Steps

The crude 8,9-dibromocyclohexadecanone was fed into a reaction vessel containing a slurry of dimethylformamide (DMF) 700 ml and lithium carbonate (111 g 1.5 mole) at 150° C. The mass was aged for 14 hrs. The reaction was washed with 2 L water then 10% aqueous acetic acid (500 ml). Distillation over caustic (2% NaOH ) affords 54 g of 7,9-cyclohexadecadien-1-one and 86 g of a mixture of 8-cyclohexadecenone and 7,9-cyclohexadecadien-1-one.

Provenance & Evidence