HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1174501Generated: October 30, 2026
Benzoic acid, 3-methyl-, methyl ester → Methyl 3-(bromomethyl)benzoate
https://huagongshe.com/reaction/1174501
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzoic acid, 3-methyl-, methyl ester | HCID 7435 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Catalyst | Benzoyl Peroxide | HCID 7187 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | Methyl 3-(bromomethyl)benzoate | HCID 517981 | 91.7% |
Reaction Steps
To a mixture of methyl-m-toluate (180 g, 1.2 mol) and N-bromosuccimide (235 g, 1.32 mol) in CCl4 (2 L) was added in portion benzoyl peroxide (18 g, 0.1 times) at 50° C. The mixture was refluxed for 5 h. Then the mixture was allowed to cool down to 40° C. and the solid was filtered off. The filtrate was concentrated to give methyl 3-(bromomethyl)benzoate (252 g, 91%) as light yellow liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07838522B2 |
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| Source dataset | uspto-grants-2010_11 |
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| ORD ID | ord-181ec4240c1f44e2a3f10bfae9c463b0 |
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| Source note | uspto-grants-2010_11 |
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