2-(Chloroacetyl)thiophene → 1004312-95-1

Participants

Reaction Steps

Analogously (3R)-3-[(3-fluorophenyl)-(3,4,5-trifluorobenzyl)carbamoyloxy]-1-(2-oxo-2-thiophen-2-yl-ethyl)-1-azoniabicyclo[2.2.2]octane chloride [Compound 7] was prepared starting from the free base of (3R)-(3-fluorophenyl)-(3,4,5-trifluorobenzyl)carbamic acid 1-aza-bicyclo[2.2.2]oct-3-yl ester by reaction with 2-chloro-1-thiophen-2-yl-ethanone.

Provenance & Evidence