4-Hydrazinobenzoic acid → 4-(3,5-dimethyl-1H-pyrazol-1-yl)benzoic acid

Participants

Reaction Steps

A solution of 4-hydrazino-benzoic acid (0.60 g, 3.95 mmol) and acetyl acetone (0.405 ml, 3.95 mmol) in ethanol (20 ml) refluxed for 1 hour. Ethanol was removed in vacuum and the remaining solid was triturated with water and collected by filtration to produce 285 (0.71 mg, 83% yield). [M−1]− 215.1.

Provenance & Evidence