HCID 59410313, compound → HCID 59410309, compound

Participants

Reaction Steps

A suspension of 5-(4-nitrophenyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester (450 mg) and palladium(II) hydroxide (20% on carbon; 0.15 g) in ethanol (30 ml) was vigorously stirred under a hydrogen atmosphere (atmospheric pressure) for 3 hours. The catalyst was then removed by filtration, and the filtrate was concentrated. The product with the molecular weight of 289.38 (C16H23N3O2); MS (ESI): 290 (M+H+) was obtained in this way.

Provenance & Evidence