Triethylamine → HCID 11271384, compound

Participants

Reaction Steps

Compound A27 was prepared in a similar manner as described above using (4-methanesulfonyl-phenyl)-[5-nitro-6-(piperidin-4-yloxy)-pyrimidin-4-yl]-amine (i.e., Compound A2) (15 mg, 0.035 mmol), triethylamine (50 μl), methanesulfonyl chloride (10 mg, 0.087 mmol), DMF (1 mL), 1H NMR (CDCl3, 400 MHz) δ 2.13 (m, 4H), 2.85 (s, 3H), 3.08 (s, 3H), 3.31 (m, 2H), 3.57 (m, 2H), 4.13 (m, 1H), 5.69 (m, 1H), 7.87 (d, 2H), 7.98 (d, 2H), 8.42 (s, 1H), 10.21 (s, 1H). Exact mass calculated for C17H21N5O7S2 471.09, found 472.3 (MH+).

Provenance & Evidence