4-Methoxycinnamic Acid → HCID 68774518, compound

HRID 1174900Notes

Reaction equation

HRID 1174900 reaction equation
[CH3:1][O:2][C:3]1[CH:13]=[CH:12][C:6](/[CH:7]=[CH:8]/[C:9]([OH:11])=O)=[CH:5][CH:4]=1.[CH3:14][N:15]([CH3:31])[CH:16]1[CH2:20][CH2:19][N:18]([C:21]2[S:22][C:23]3[CH:29]=[C:28]([NH2:30])[CH:27]=[CH:26][C:24]=3[N:25]=2)[CH2:17]1>>[CH3:14][N:15]([CH3:31])[CH:16]1[CH2:20][CH2:19][N:18]([C:21]2[S:22][C:23]3[CH:29]=[C:28]([NH:30][C:9](=[O:11])[CH:8]=[CH:7][C:6]4[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:13][CH:12]=4)[CH:27]=[CH:26][C:24]=3[N:25]=2)[CH2:17]1

Participants

3

Reactant 2

HCID 6994144-Methoxycinnamic AcidHCID 632315072-(3-Dimethylamino-pyrrolidin-1-yl)-benzothiazol-6-ylamine

Product 1

HCID 68774518HCID 68774518, compoundYield 6%

Procedure

Prepare according to Method B, using trans-4-methoxycinnamic acid (112 mg, 0.629 mmol) and 2-(3-dimethylamino-pyrrolidin-1-yl)-benzothiazol-6-ylamine (162 mg, 0.618 mmol) to afford the title compound (15 mg, 6%). mass spectrum (m/e): 423.3 [M+H], 421.3 [M−H].

Workup

  1. customPrepare

Sources & evidence

ORD record
ord-7d6956c1e1f64e8fbb53fb49e87a1e9e
Source dataset
uspto-grants-2010_11
Patent number
US07838543B2

Reaction notes

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