HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl-(1-methyl-piperidin-4-yl)-(5-nitro-benzooxazol-2-yl)-amine → N2-Methyl-N2-(1-methyl-piperidin-4-yl)-benzooxazole-2,5-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl-(1-methyl-piperidin-4-yl)-(5-nitro-benzooxazol-2-yl)-amine | HCID 59558006 | — |
| Catalyst | Iron | HCID 23925 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | N2-Methyl-N2-(1-methyl-piperidin-4-yl)-benzooxazole-2,5-diamine | HCID 59558009 | — |
Reaction Steps
The title compound was prepared according to the procedure described in General Method B, using methyl-(1-methyl-piperidin-4-yl)-(5-nitro-benzooxazol-2-yl)-amine (0.583 g, 2.01 mmol), acetic acid (8 mL), and iron (1.12 g, 20.1 mmol) to provide product (0.474 g, 91%). mass spectrum (m/e): 261.2 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07838543B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-82502ca5291d42889b5949d5f19b64f2 |
| Source note | uspto-grants-2010_11 |