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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1174962Generated: October 25, 2026

Piperidine, 1-(2-chloroethyl)-, hydrochloride → Methyl-(6-nitro-benzothiazol-2-yl)-(2-piperidin-1-yl-ethyl)-amine

https://huagongshe.com/reaction/1174962

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidine, 1-(2-chloroethyl)-, hydrochlorideHCID 74826—
ReactantN-Methyl-6-nitrobenzo[D]thiazol-2-amineHCID 638568—
ProductMethyl-(6-nitro-benzothiazol-2-yl)-(2-piperidin-1-yl-ethyl)-amineHCID 57771692—

Reaction Steps

The title compound is prepared according to the general procedure outlined in Example 61, Step 2, utilizing methyl(6-nitro-benzothiazol-2-yl)-amine (979 mg, 4.68 mmol) and N-(2-chloroethyl)-piperidine hydrochloride (2.01 g, 10.92 mmol) to yield 1.43 g (79%) of the product. mass spectrum (ion-spray): (m/z)=321.3 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07838543B2
Source datasetuspto-grants-2010_11
ORD IDord-bc555665845446f3bc46efa0a9d15277
Source noteuspto-grants-2010_11