4-Cyclohexylbenzoic acid → HCID 11495811, compound

HRID 1174966Notes

Reaction equation

HRID 1174966 reaction equation
[CH:1]1([C:7]2[CH:15]=[CH:14][C:10]([C:11]([OH:13])=O)=[CH:9][CH:8]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:16][N:17]([CH3:32])[CH2:18][CH2:19][N:20]([CH3:31])[C:21]1[S:22][C:23]2[CH:29]=[C:28]([NH2:30])[CH:27]=[CH:26][C:24]=2[N:25]=1>>[CH:1]1([C:7]2[CH:8]=[CH:9][C:10]([C:11]([NH:30][C:28]3[CH:27]=[CH:26][C:24]4[N:25]=[C:21]([N:20]([CH2:19][CH2:18][N:17]([CH3:16])[CH3:32])[CH3:31])[S:22][C:23]=4[CH:29]=3)=[O:13])=[CH:14][CH:15]=2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 883374-Cyclohexylbenzoic acidHCID 55226563N2-(2-Dimethylamino-ethyl)-N2-methyl-benzothiazole-2,6-diamine

Product 1

HCID 11495811HCID 11495811, compound

Procedure

The title compound is prepared by following General Method A, using 4-cyclohexyl-benzoic acid (0.16 g, 0.78 mmol), and N*2*-(2-Dimethylamino-ethyl)-N*2*-methyl-benzothiazole-2,6-diamine (0.15 g, 0.60 mmol) to afford a white solid (0.076 g, 29%). LC/MS: Retention time 5.00 min; (m/z): calcd for C25H32N4OS (M+H)+: 437.6; found: 437.0.

Sources & evidence

ORD record
ord-251a4d8ec4f342a783e61037bcaec218
Source dataset
uspto-grants-2010_11
Patent number
US07838543B2

Reaction notes

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