HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-[1,1'-biphenyl]-4-carboxylic acid → 2-Methyl-biphenyl-4-carboxylic acid {2-[(2-dimethylamino-ethyl)-methyl-amino]-benzothiazol-6-yl}-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-[1,1'-biphenyl]-4-carboxylic acid | HCID 21521810 | — |
| Reactant | N2-(2-Dimethylamino-ethyl)-N2-methyl-benzothiazole-2,6-diamine | HCID 55226563 | — |
| Product | 2-Methyl-biphenyl-4-carboxylic acid {2-[(2-dimethylamino-ethyl)-methyl-amino]-benzothiazol-6-yl}-amide | HCID 57771721 | — |
Reaction Steps
The title compound is prepared by following General Method A, using 2-methyl-biphenyl-4-carboxylic acid (0.072 g, 0.34 mmol), and N*2*-(2-dimethylamino-ethyl)-N*2*-methyl-benzothiazole-2,6-diamine (0.065 g, 0.26 mmol) to give 0.036 g, (31%) of product. LC/MS: Retention time=4.80 min; (m/z): calcd for C2H28N4OS (M+H)+: 445.6; found: 445.0.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07838543B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-82b155a208a64f2d865068f7ab8e4b17 |
| Source note | uspto-grants-2010_11 |