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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1174970Generated: October 27, 2026

2-Methyl-[1,1'-biphenyl]-4-carboxylic acid → 2-Methyl-biphenyl-4-carboxylic acid {2-[(2-dimethylamino-ethyl)-methyl-amino]-benzothiazol-6-yl}-amide

https://huagongshe.com/reaction/1174970

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-[1,1'-biphenyl]-4-carboxylic acidHCID 21521810—
ReactantN2-(2-Dimethylamino-ethyl)-N2-methyl-benzothiazole-2,6-diamineHCID 55226563—
Product2-Methyl-biphenyl-4-carboxylic acid {2-[(2-dimethylamino-ethyl)-methyl-amino]-benzothiazol-6-yl}-amideHCID 57771721—

Reaction Steps

The title compound is prepared by following General Method A, using 2-methyl-biphenyl-4-carboxylic acid (0.072 g, 0.34 mmol), and N*2*-(2-dimethylamino-ethyl)-N*2*-methyl-benzothiazole-2,6-diamine (0.065 g, 0.26 mmol) to give 0.036 g, (31%) of product. LC/MS: Retention time=4.80 min; (m/z): calcd for C2H28N4OS (M+H)+: 445.6; found: 445.0.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07838543B2
Source datasetuspto-grants-2010_11
ORD IDord-82b155a208a64f2d865068f7ab8e4b17
Source noteuspto-grants-2010_11