4-(2-Chloro-4-methoxyphenyl)benzoic acid → 2'-Chloro-4'-methoxy-biphenyl-4-carboxylic acid {2-[methyl-(1-methyl-pyrrolidin-3-yl)-amino]-benzothiazol-6-yl}-amide

Participants

Reaction Steps

The title compound is prepared by following Method A, using 2′-chloro-4′-methoxy-biphenyl-4-carboxylic acid (0.26 g, 0.99 mmol), and isomer-1 of N*2*-Methyl-N*2*-(1-methyl-pyrrolidin-3-yl)-benzothiazole-2,6-diamine (0.20 g, 0.76 mmol) to afford the product (0.125 g, 32%). LC/MS: Retention time=5.27 min; (m/z): calcd for C27H27ClN4O2S. m/e: 507.1; found: 507.0.

Provenance & Evidence