4-Cyclohexyloxybenzoic acid → HCID 11705122, compound

HRID 1174978Notes

Reaction equation

HRID 1174978 reaction equation
[CH:1]1([O:7][C:8]2[CH:16]=[CH:15][C:11]([C:12]([OH:14])=O)=[CH:10][CH:9]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:17][N:18]([CH3:33])[CH2:19][CH2:20][N:21]([CH3:32])[C:22]1[S:23][C:24]2[CH:30]=[C:29]([NH2:31])[CH:28]=[CH:27][C:25]=2[N:26]=1>>[CH:1]1([O:7][C:8]2[CH:9]=[CH:10][C:11]([C:12]([NH:31][C:29]3[CH:28]=[CH:27][C:25]4[N:26]=[C:22]([N:21]([CH2:20][CH2:19][N:18]([CH3:17])[CH3:33])[CH3:32])[S:23][C:24]=4[CH:30]=3)=[O:14])=[CH:15][CH:16]=2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 673174-Cyclohexyloxybenzoic acidHCID 55226563N2-(2-Dimethylamino-ethyl)-N2-methyl-benzothiazole-2,6-diamine

Product 1

HCID 11705122HCID 11705122, compound

Procedure

The title compound is prepared by following Method A, using 4-cyclohexyloxy benzoic acid (0.20 g, 0.91 mmol), and N*2*-(2-Dimethylamino-ethyl)-N*2*-methyl-benzothiazole-2,6-diamine (0.17 g, 0.68 mmol) to afford the 0.15 g (36%). LC/MS: Retention time=5.23 min; (m/z): calcd for C25H32N4O2S: 453.6; found: 453.0.

Workup

  1. customto afford the 0.15 g (36%)

Sources & evidence

ORD record
ord-5cf91bd44f904bf2b53db4216a2c3f11
Source dataset
uspto-grants-2010_11
Patent number
US07838543B2

Reaction notes

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