2-Chloro-4-methoxybenzeneboronic acid → 5-(2-Chloro-4-methoxy-phenyl)-pyrazine-2-carboxylic acid {2-[(2-dimethylamino-ethyl)-methyl-amino]-benzothiazol-6-yl}-amide

참여 물질

반응 단계

The title compound is prepared by following a procedure analogous to Example 113, Step 1, using 5-chloro-pyrazine-2-carboxylic acid {2-[(2-dimethylamino-ethyl)-methyl-amino]-benzothiazol-6-yl}-amide (0.10 g, 0.26 mmol) and 2-chloro-4-methoxy-phenyl boronic acid (0.057 g, 0.31 mmol) to afford 0.062 g (48%). LC/MS, Retention time=4.89 nm in; (m/z): calcd for C24H25ClN6O2S: 497.0; found: 499.0.

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