HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-chlorophenyl)-1H-imidazole → 4-[2-(4-Chloro-phenyl)-imidazol-1-yl]-3-hydroxy-2,2-dimethyl-chroman-6-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-chlorophenyl)-1H-imidazole | HCID 242948 | — |
| Reactant | 2,2-Dimethyl-3,4-epoxy-6-cyanochroman | HCID 10867360 | — |
| Product | 4-[2-(4-Chloro-phenyl)-imidazol-1-yl]-3-hydroxy-2,2-dimethyl-chroman-6-carbonitrile | HCID 66700179 | — |
Reaction Steps
Following the procedure in Example 1, using (±)-2,2-dimethyl-1a,7b-dihydro-2H-1,3-dioxa-cyclopropa[a]naphthalene-6-carbonitrile and 2-(4-chloro-phenyl)-1H-imidazole as starting materials, the title compounds were prepared as white solids.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07838553B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-9afdab55a19a4250a21874115d39d4cc |
| Source note | uspto-grants-2010_11 |