6-(4-Chlorophenyl)-2,3-dihydropyridazin-3-one → HCID 16048740, compound

HRID 1175015Notes

Reaction equation

HRID 1175015 reaction equation
[CH3:1][C:2]1([CH3:15])[O:11][C:10]2[C:5](=[CH:6][C:7]([C:12]#[N:13])=[CH:8][CH:9]=2)[CH:4]2O[CH:3]12.[Cl:16][C:17]1[CH:22]=[CH:21][C:20]([C:23]2[CH:24]=[CH:25][C:26](=[O:29])[NH:27][N:28]=2)=[CH:19][CH:18]=1>>[Cl:16][C:17]1[CH:18]=[CH:19][C:20]([C:23]2[CH:24]=[CH:25][C:26](=[O:29])[N:27]([C:4]3[C:5]4[C:10](=[CH:9][CH:8]=[C:7]([C:12]#[N:13])[CH:6]=4)[O:11][C:2]([CH3:15])([CH3:1])[CH:3]=3)[N:28]=2)=[CH:21][CH:22]=1

Participants

3

Procedure

Following the procedure in Example 1, using (±)-2,2-dimethyl-1a,7b-dihydro-2H-1,3-dioxa-cyclopropa[a]naphthalene-6-carbonitrile and 6-(4-Chloro-phenyl)-2H-pyridazin-3-one as starting materials, the title compound were prepared as white solids.

Sources & evidence

ORD record
ord-24912310f7b343a6ab05209c1fbb63e9
Source dataset
uspto-grants-2010_11
Patent number
US07838553B2

Reaction notes

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