HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-fluorobenzothiazole → 4-(5-Fluoro-benzothiazol-2-ylamino)-3-hydroxy-2,2-dimethyl-chroman-6-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-fluorobenzothiazole | HCID 821203 | — |
| Reactant | 2,2-Dimethyl-3,4-epoxy-6-cyanochroman | HCID 10867360 | — |
| Product | 4-(5-Fluoro-benzothiazol-2-ylamino)-3-hydroxy-2,2-dimethyl-chroman-6-carbonitrile | HCID 86611014 | — |
Reaction Steps
Following the procedure in Example 1, using (±)-2,2-dimethyl-1a,7b-dihydro-2H-1,3-dioxa-cyclopropa[a]naphthalene-6-carbonitrile and 5-fluoro-benzothiazol-2-ylamine as starting material, the title compound was prepared as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07838553B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-8818ac8d785742cba92e010496738cdd |
| Source note | uspto-grants-2010_11 |