HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1aS,7bS)-2,2-Dimethyl-1a,7b-dihydro-2H-oxireno[2,3-c]chromene-6-carbonitrile → (3S,4R)-3-Hydroxy-2,2-dimethyl-4-(quinazolin-4-yloxy)-chroman-6-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1aS,7bS)-2,2-Dimethyl-1a,7b-dihydro-2H-oxireno[2,3-c]chromene-6-carbonitrile | HCID 9837089 | — |
| Reactant | HCID 178517962 | HCID 178517962 | — |
| Product | (3S,4R)-3-Hydroxy-2,2-dimethyl-4-(quinazolin-4-yloxy)-chroman-6-carbonitrile | HCID 66699851 | — |
Reaction Steps
Following the procedure in Example 1, using (S,S)-2,2-dimethyl-1a,7b-dihydro-2H-1,3-dioxa-cyclopropa[a]naphthalene-6-carbonitrile and quinazolin-4-ol as starting material, the title compound was prepared as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07838553B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-403b3ed1133a48738f52272ddcead006 |
| Source note | uspto-grants-2010_11 |