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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1175045Generated: November 3, 2026

6-(4-Chlorophenyl)-2,3-dihydropyridazin-3-one → 6-(4-Chloro-phenyl)-2-(3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-pyrano[3,2-c]pyridin-4-yl)-2H-pyridazin-3-one

https://huagongshe.com/reaction/1175045

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(4-Chlorophenyl)-2,3-dihydropyridazin-3-oneHCID 689085—
Reactant3,4-dihydro-2,2-dimethyl-3,4-epoxy-2H-pyrano[3,2-c]pyridineHCID 10856030—
Product6-(4-Chloro-phenyl)-2-(3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-pyrano[3,2-c]pyridin-4-yl)-2H-pyridazin-3-oneHCID 66700004—

Reaction Steps

Following the procedure in Example 1, using (±)-2,2-dimethyl-1a,7b-dihydro-2H-1,3-dioxa-6-aza-cyclopropa[a]naphthalene and 6-(4-chloro-phenyl)-2H-pyridazin-3-one as starting materials, the title compound was prepared as a pale yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07838553B2
Source datasetuspto-grants-2010_11
ORD IDord-00a52c2900584ea0a0b861afbd5e7c94
Source noteuspto-grants-2010_11