Thiophosgene → 5-Bromo-6-isothiocyanatoquinoxaline

HRID 1175050Notes

Reaction equation

HRID 1175050 reaction equation
Br.[NH2:2][C:3]1[C:4]([Br:13])=[C:5]2[C:10](=[CH:11][CH:12]=1)[N:9]=[CH:8][CH:7]=[N:6]2.[C:14](Cl)(Cl)=[S:15]>O>[Br:13][C:4]1[C:3]([N:2]=[C:14]=[S:15])=[CH:12][CH:11]=[C:10]2[C:5]=1[N:6]=[CH:7][CH:8]=[N:9]2

Participants

4

Reactant 2

HCID 10040ThiophosgeneHCID 183506656-Amino-5-bromoquinoxaline hydrobromide

Product 1

HCID 44602745-Bromo-6-isothiocyanatoquinoxaline

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a stirred solution of 6-amino-5-bromoquinoxaline hydrobromide (10 g) in distilled water (150 ml) is added thiophosgene (3 ml). The solution is stirred for two hours at room temperature and the resultant precipitate is collected by filtration, washed with water, and dried to afford 5-bromo-6 -isothiocyanato-quinoxaline.

Workup

  1. filtrationthe resultant precipitate is collected by filtration
  2. washwashed with water
  3. customdried

Sources & evidence

ORD record
ord-41b560cd1f6b4c51a556ea8ca3ecc91b
Source dataset
uspto-grants-2010_11
Patent number
US07838563B2

Reaction notes

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