Morpholine → HCID 59558467, compound

HRID 1175176Notes

Reaction equation

HRID 1175176 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1F)[C:5]#[N:6].[NH:11]1[CH2:16][CH2:15][O:14][CH2:13][CH2:12]1>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[N:11]1[CH2:16][CH2:15][O:14][CH2:13][CH2:12]1)[C:5]#[N:6]

Participants

3

Reactant 2

HCID 8083MorpholineHCID 1455253-Chloro-4-fluorobenzonitrile

Product 1

HCID 59558467HCID 59558467, compound

Procedure

3-Chloro-4-morpholin-4-yl-benzonitrile is synthesized starting from 3-Chloro-4-fluoro-benzonitrile and morpholine as described in Example 306. LC-MS (m/z, ES+): 223 (MH+), Retention time: 1.11 mins (LC-MS method 7)

Sources & evidence

ORD record
ord-70a1f9b355204b1a9625ff1fb1849f08
Source dataset
uspto-grants-2010_11
Patent number
US07838674B2

Reaction notes

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